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Digital Pathology

The versatile digital pathology solution that meets your evolving needs to keep you ahead of the curve

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Versatility that fits
any workflow

Quality and Consistency

Customizable solutions to meet your laboratory needs

Accelerate your analysis to reach your answer
with greater ease

Explore our Workflow Options

Uncover a solution that fits your needs

Whole-Slide Scanners

Pannoramic 1000

Pannoramic 1000

BF

1000 slide FLASH scanning for high volume and high throughput labs that don't want to sacrifice flexibility and quality.

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Pannoramic 480

Pannoramic 480

BF

480 slide scanning for labs that require reliable and automated high through-put while maintaining image quality and flexibility

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Pannoramic 250 Flash III

Pannoramic 250 Flash III

BF FL

For labs that demand BF and/or FL scanning on the same platform with award winning quality and continuous loading of up to 300 slides at FLASH technology speeds.

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Pannoramic SCAN II

Pannoramic SCAN II

BF FL

For labs that need BF and FL scanning, with continuous workflow loading capabilities of up to 150 slides at a time.

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Pannoramic MIDI II

Pannoramic MIDI II

BF FL

For labs that need a compact, flexible scanner with BF and FL scanning capabilities of 12 slide batches.

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Pannoramic DESK II

Pannoramic DESK II

BF

For labs that need the highest quality imaging capabilities for their remote and frozen section workflow.

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Software Solutions

Software solutions provided by Epredia offers pathologists, laboratorians and IT staff with scalable integration and interoperability for an evolving technology landscape.

IMS Software
SlideCenter

SlideCenter

A powerful, server or cloud based image management system for storing both macroscopic and digital slide images.

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CaseManager

CaseManager

A collaborative digital pathology workflow solution, that provides pathologists with full control and visibility of their routine work.

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Viewing Software
SlideViewer

SlideViewer

Provides researchers and pathologists with a flexible and next generation image viewing experience.

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IA Software
QuantCenter

QuantCenter

A multi-module image analysis platform designed for image quantification in histopathology, FISH and molecular pathology.

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AI Software
Aiforia

Aiforia

Equips pathologists and scientists in preclinical and clinical labs with powerful deep learning and cloud-based technology to advance their image analysis tasks and workflows.

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Paige

Paige

Provides additional information from digital slides to help pathologists and scientists perform their diagnostic work efficiently and confidently.

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Using Digital Whole Slide Scanning of Liver Tissue and AI-Enabled, Quantitative Histopathological Analysis

The study described in this paper is the result of a unique collaboration between several companies with combined goals of providing the NASH research community with a time-efficient, flexible, off-the-shelf diet-induced mouse NASH B6 Model (Taconic Biosciences, Inc.) that can be utilized in directed research studies for therapeutic drug development (Explora BioLabs).

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Laser optimized cassettes

For research and education use only, not for use in diagnostic procedures in the U.S. This product has not been approved or cleared as a medical device by the U.S. Food and Drug Administration. For Europe this product has been designed for diagnostic purposes, although the medical device registration process is pending in Europe.

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Pannoramic 1000
Pannoramic 480
Pannoramic 250 Flash III
Pannoramic SCAN II
Pannoramic MIDI II
Pannoramic DESK II
SlideCenter
CaseManager
Slideviewer
QuantCenter
Aiforia
Paige

See why users love the Pannoramic 1000.

Market Leading in Capacity

Largest-capacity, whole-slide scanner on the market: 1000 standard-width slides.

Impressive Speed

Can scan 15x15 mm slide area in 30 seconds (20x objective (40x optical equivalent), 0.25 µm/pixel, single layer).

Touch Interface

Touch-enabled, easy-to-use software interface.

Double-width Slide Compatible

Double-width slide capacity (optional).

Automated detection

Automated tissue detection and coverslip detection.

Slide Position Allocation

Flexible Priority/STAT slide position allocation.

Impressive Speed

Multilayer (Z-stack) and Extended Focus scanning (optional).

3 Objectives, Exchangeable During Scanning

Three individual objectives exchangeable automatically during scanning.

1D and 2D

1D and 2D barcode reading and parsing.

When speed is your need. Free up your laboratory's resources with the new Pannoramic 1000 - the high-throughput whole-slide scanning solution.

See why users love the Pannoramic 480.

Market Leading in Capacity

Largest-capacity, whole-slide scanner on the market: 480 standard-width slides.

Impressive Speed

Can scan 15x15 mm slide area in 30 seconds (20x objective (40x optical equivalent), 0.25 µm/pixel, single layer).

Touch Interface

Touch-enabled, easy-to-use software interface.

Double-width Slide Compatible

Double-width slide capacity (optional).

Automated detection

Automated tissue detection and coverslip detection.

Slide Position Allocation

Flexible Priority/STAT slide position allocation.

Impressive Speed

Multilayer (Z-stack) and Extended Focus scanning (optional).

3 Objectives, Exchangeable During Scanning

Three individual objectives exchangeable automatically during scanning.

1D and 2D

1D and 2D barcode reading and parsing.

See why users love the Pannoramic 250 Flash III.

  • 300-slide capacity and continuous loading with vertical slide arrangement.
  • Award-winning, exceptional image quality for both brightfield and up to nine fluorescent filter positions available for single and multiple band cubes with advanced FISH scanning technique.
  • Pulsed Xenon FLASH light source for high-speed brightfield scanning.
  • Up to 90x brightfield and 60x fluorescent magnification by default.
  • Darkfield preview for easy localization of fluorescent samples.
  • Brightfield slide scanning in one minute at 40x resolution.
  • Motorized objective and camera changer.
  • Automatic slide loading, previewing, barcode reading and scanning.
  • All-around system for high volume slide scanning.

See why users love the Pannoramic SCAN II.

  • 150-slide capacity and continuous loading with vertical slide arrangement.
  • Exceptional image quality for both brightfield and up to nine fluorescent filter positions available for single and multiple band cubes with advanced FISH scanning technique.
  • Up to 90x brightfield and fluorescent magnification by default.
  • Motorized objective changer.
  • One high-quality monochrome camera is used for both brightfield and fluorescence with unique three-channel brightfield light source.
  • Automatic slide loading, previewing, barcode reading and scanning.
  • All-around system for high-volume slide scanning.

See why users love the Pannoramic MIDI II.

  • Twelve-slide capacity and continuous loading with horizontal slide arrangement.
  • Brightfield and up to nine fluorescent filter positions available for single and multiple band cubes.
  • Up to 90x brightfield and fluorescent magnification.
  • Motorized objective changer.
  • One high-quality monochrome camera is used for both brightfield and fluorescence with unique three-channel brightfield light source.
  • Automatic slide loading, previewing, barcode reading and scanning.

See why users love the Pannoramic DESK II.

  • Double-wide slide capacity.
  • Brightfield only scanning.
  • 40x magnification by default, up to 70x.
  • Manual slide loading, automatic previewing, barcode reading and scanning.
  • Small footprint.

Feature packed. See why our users love SlideCenter.

  • Web-based slide and case database with fast search.
  • Slide access through the free SlideViewer, the InstantViewer or the iPad Viewer.
  • Virtual Slide handling.
  • MS Network, HTTP and HTTPS accessibility.
  • Fully manageable user and user group rights system.
  • Direct scanning into database with PANNORAMIC digital slide scanners.
  • Macro images and multiple file attachments stored in the case.
  • SlideCenter can work with other 3DHISTECH software applications (e.g. quantification software can be run on remote slides).

New Features (SlideCenter 3.1)

  • New Invicro integration.
  • Storing 100+ slides in a single folder is now possible.
  • Server-side Quick Search: The Quick Search funtion now works on the server side.
  • Database version update to PostgreSQL version 12.6 for optimal and safe operations.

Feature packed. See why our users love CaseManager.

  • Sending special examination requests to the laboratory information system.
  • Integration with ClinicalViewer: Patient and staining data from CaseManager is displayed on the top of the viewer’s user interface.
  • Integration with IVD approved Diagnostic Applications: Results of the automated image analysis are displayed in CaseManager.
  • Communication with 3DHISTECH’s CentralLogService application to log user and system activity.
  • Multi-purpose digital pathology workflow support: CaseManager supports the digital pathology workflow with final report in the fields of histopathology, molecular pathology, cytology, and autopsy.
  • With Focus View, all details of a case are displayed on a single screen. Such details include patient data, additional cases related to the patient, diagnosis codes, digital slides, attachments, and the final report, and more.
  • DICOM file handling format supported.
  • Slide archiving option to a PACS server.

Feature packed. See why our users love SlideViewer.

Easy slide viewing and navigation

  • A simple and straightforward graphical user interface, suited for viewing brightfield, fluorescence and confocal slides.
  • MultiView: A maximum of nine slides of a single case with different stainings can be viewed simultaneously on the main screen.
  • Case preview: A slide preview panel with all slides within a case is integrated into the main screen.
  • Slide stack visualization: Slides of serial sections with different stainings can be organized and then aligned in a slide stack.

Advanced file management

  • SlideViewer opens several 3rd party digital slides: SVS files (Aperio by Leica Biosystems) and NDP, VMS, VMU files (Hamamatsu) and supports multiple file export formats: DICOM (optional) TIFF, JPEG, SVS, MRXS.

Feature packed. See why our users love QuantCenter.

Molecular pathology


FISHQuant

  • A powerful cancer and cytogenetic application dedicated to quantify FISH (Fluorescence in Situ Hybridization) signals on tissue samples of solid tumor diseases such as: breast and lung cancer, sarcomas, and lymphomas.
  • This module is suitable for examination of hematological tumors, FISHQuant classifies the interphase and metaphase cells individually for a comprehensive evaluation.

CISHQuant

  • Quantify CISH (Chromogenic In Situ Hybridization) stained samples. The algorithm can be calibrated to the stain protocol and quantify by using an integrated color setting tool. This module is suitable for examining gene amplification deletion and chromosome aberration.

CISH-RNAQuant

  • Detects RNA virus in virus-infected cell nuclei (Epstein-Barr virus, HPV, HHV8).
  • The application contains a color adjustment module which can be calibrated to the applied stain protocol and quality.

FISH Quantification


  • Cancer and cytogenetic application.
  • FISH quantification on tissue samples of solid tumor diseases, like: breast cancer, lung cancer, sarcoma symptoms, lymphomas.
  • For hematology type tumors, 3DHISTECH’s FISHQuant application scores the interphase and metaphase cells individually for an even more comprehensive evaluation.
  • Autofluorescence filtering for FISH (Fluorescence in situ hybridization) samples. As part of QuantCenter, FISHQuant provides a user-friendly, standardized interface and easy navigation bar.
  • Renewed algorithm for a more sensitive segmentation of nuclei and spots.
  • Brand new data handling.
  • Benefit from the fast and safe data processing, easy data visualization and precise data filtering.

IHC Quantification


NuclearQuant

  • A cell nuclei detection module designed for cell nuclei detection and quantification of IHC stained samples. The algorithm can be calibrated to the stain quality (local laboratory protocol or different stainer) by using an integrated color setting tool.

MembraneQuant

  • A membrane detection software application can be used for IHC stained histological sample quantification. The algorithm can be calibrated to the stain quality (local laboratory protocol or different stainer) by using an integrated color setting tool.

CellQuant

  • A cell detection application which is optimal for several IHC quantification.
  • The application is adequate for cell nuclei, cytoplasmatic and membrane marker quantification. The software reports results based on dedicated scores and positivity ratings of cell nuclei, cytoplasm or membrane signals.

DensitoQuant

  • An easy to use, fast and accurate, stain-intensity-based IHC quantification tool.
  • The application identifies the positive stain, based on an automatic color separation method through which individual positive pixels are counted and classified based on intensity and threshold ranges.

Feature packed. See why our users love Aiforia.

The cloud based Aiforia products and services aim to escalate the efficiency and precision of medical image analysis beyond current capabilities, across a variety of fields from oncology to neuroscience and more.

Feature packed. See why our users love Paige.

The Paige portfolio includes the Paige Platform, a comprehensive imaging solution comprised of a fast, zero-footprint viewer, storage capabilities and AI-based diagnostic software to help pathologists review cases and support their overall workflow.

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Pannoramic Digital Pathology Scanners

  Technical Specifications
  Pannoramic DESK II Pannoramic MIDI II Pannoramic SCAN II Pannoramic 250 FLASH III Pannoramic 1000
Slide loading capacity 1 12 150 or continuous loading 250 or continuous loading 1000
Double-width slide compatible Yes No Yes
Objective type 20x (NA 0.8) or 40x (NA 0.95) 20x (NA 0.8) and 40x (NA 0.95)
Brightfield scanning technology 5 MP 12-bit camera with RGB illumination (3-chip equivalent) 5 MP 12-bit or 4.2 MP 16-bit camera with RGB illumination (3-chip equivalent) 12 MP 12-bit camera with Xenon Flash illumination
Optical magnification 58x 52x and 110x / 31x and 62x 41x/82x
Highest brighffield scanning speed* 6 min 30 sec 3 min 23 sec 2 min 30 sec 35 Sec (20x) / 1 Min 35 Sec (40X) 30 Sec (20x or 40x)
Average BF file size (native resolution) 2.6 GB (20x) / 7.9 GB (40x) 1.2 GB (20x) / 3.7 GB (40x) 1.25 GB (20x) / 4.5 GB (40x)
Highest throughput/hour -- 15 20 60 72
Fluorescence scanning technology -- 4.2 MP 16-bit camera with wideband / 6-channel LED Additional 4.2 MP 16-bit camera with 6-channel LED --
Highest fluorescence scanning speed** -- 6 min @ 31x
22 min @ 62x
5 min @ 31x
15 min @ 62x
--
Dimensions (Wx DxH, cm) 38 x 31 x25 70 x 50 x 50 74 x 53 x 45 68 x 69 x 55 154 x 100 x 91
Weight (kg) 12 23 26 46 270
Technical Specifications Pannoramic DESK II Pannoramic MIDI II Pannoramic SCAN II Pannoramic 250 FLASH III Pannoramic 1000
Slide loading capacity 1 12 150 or continuous loading 250 or continuous loading 1000
Double-width slide compatible Yes No No No Yes
Objective type 20x (NA 0.8) or 40x (NA 0.95) 20x (NA 0.8) and 40x (NA 0.95) 20x (NA 0.8) and 40x (NA 0.95) 20x (NA 0.8) and 40x (NA 0.95) 20x (NA 0.8) and 40x (NA 0.95)
Brightfield scanning technology 5 MP 12-bit camera with RGB illumination (3-chip equivalent) 5 MP 12-bit or 4.2 MP 16-bit camera with RGB illumination (3-chip equivalent) 5 MP 12-bit or 4.2 MP 16-bit camera with RGB illumination (3-chip equivalent) 12 MP 12-bit camera with Xenon Flash illumination 12 MP 12-bit camera with Xenon Flash illumination
Optical magnification 58x 52x and 110x / 31x and 62x 52x and 110x / 31x and 62x 41x/82x 41x/82x
Highest brighffield scanning speed* 6 min 30 sec 3 min 23 sec 2 min 30 sec 35 Sec (20x) / 1 Min 35 Sec (40X) 30 Sec (20x or 40x)
Average BF file size (native resolution) 2.6 GB (20x) / 7.9 GB (40x) 2.6 GB (20x) / 7.9 GB (40x) 1.2 GB (20x) / 3.7 GB (40x) 1.25 GB (20x) / 4.5 GB (40x) 1.25 GB (20x) / 4.5 GB (40x)
Highest throughput/hour -- 15 20 60 72
Fluorescence scanning technology -- 4.2 MP 16-bit camera with wideband / 6-channel LED 4.2 MP 16-bit camera with wideband / 6-channel LED Additional 4.2 MP 16-bit camera with 6-channel LED --
Highest fluorescence scanning speed** -- 6 min @ 31x
22 min @ 62x
6 min @ 31x
22 min @ 62x
5 min @ 31x
15 min @ 62x
--
Dimensions (Wx DxH, cm) 38 x 31 x25 70 x 50 x 50 74 x 53 x 45 68 x 69 x 55 154 x 100 x 91
Weight (kg) 12 23 26 46 270

* 15 x 15 mm area

** 10x10 mm area, 3 filters, 20 ms exposure

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Disclaimers

FDA Disclaimer

During the COVID-19 pandemic duration, the U.S. FDA guidelines for digital pathology have been amended to allow for digital pathology solutions* in remote settings, that are not currently 510(k) cleared for diagnostics. We are ready to assist you with a special solution that includes a 3DHISTECH Pannoramic 1000 whole slide scanner with CaseCenter and CaseManager software, along with the integration services for a special package price.

Due to the need for compliance with the FDA, this offer is only available to U.S. customers. No modifications to the scanner and software are possible for this remote clinical purpose.

For research use only, not for use in diagnostic procedure.

This product is not available in all regions.

Please reach out to your local sales representative for more information

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